Emergency services rushed to a house on Church Road in the small village of Kirby Muxlow in the early hours of Friday after receiving reports of a fire.
Two people fell victim of the blaze, police said, adding they launched an investigation looking into what the cause of the blaze.
A Leicestershire Police spokesman said: “We were called at 3.30am this morning by the fire service reporting their attendance at a house fire on Church Road in Kirby Muxloe.
“Officers and the ambulance service attended the scene.
“A woman and a man were pronounced dead at the scene.”
The officer added the pair haven’t been identified yet.
He added: “Formal identification of the deceased has not yet taken place.
“A cordon is in place and an investigation into the circumstances of the deaths is continuing.”
People said to have heard an “explosion” and seen flames devouring the house.
A neighbour said: “My brother got up about 4am and heard an explosion.
“My mum woke up at just after 4am and saw the house going up in flames.”
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