Stoke-on-Trent, too, could find itself in tier 3 – with a rate per 100,000 population of 532.8.
In Bolton, the rate is 412.8 while Blackburn with Darwen’s rate has reached 470.3.
Manchester, which previously refused to enter Tier 3 restrictions without additional cash form the Goverment, is seeing higher than average rates.
Greater Manchester Mayor Andy Burnham said while infection rates were dropping, the Government should not “let everything loose”.
He told BBC Breakfast: “I would also say to the Government, don’t just go towards Christmas and let everything loose.
“What you need to do is keep a steady approach that will keep the numbers going in the way they are currently going in the North West and in Greater Manchester, and that will relieve the pressures on the NHS come January.”